Answer to Question #224160 in Organic Chemistry for Prince

Question

1)When furan is treated with the mixture of hcn and hcl?
2)When furan treated with maleic anhydride?
3) discuss fischer indole synthesis

Answer 1

1)Pyrroles and furans also undergo the Gattermann aldehyde synthesis: with HCl and HCN, furan gives furfuraldehyde.

2)Furan reacts as a diene with powerful dienophiles like maleic anhydride, maleimide and benzyne to give Diels–Alder adducts.MALEIC ANHYDRIDE react vigorously on contact with oxidizing materials. Reacts exothermically with water or steam.

3)The Fischer indole synthesis is an organic reaction used to convert a phenyl hydrazine and an aldehyde or ketone to an indole using an acid catalyst. The mechanism begins with formation of a phenylhydrazone through the acid catalyzed reaction of the hydrazine with the carbonyl.