Answer to Question #196665 in Organic Chemistry for saiful

Question

Km of Hexokinase enzyme for the glucose is 0.15 mM and Glucokinase is 2 mM”. Discuss this statement in terms of the significance of glucose metabolism. 

Answer 1

Glucokinase and Hexokinase are enzymes which phosphorylate glucose to glucose-6-phosphate, trapping glucose inside the cell.Compared to hexokinase, glucokinase has a higher Km (lower binding affinity) and a higher Vmax (increased capacity).