Synthesis of 2 methylpentanoic acid from malonic ester
1) EtO(O)CCH2C(O)OEt 1. + CH3ONa, 2. + CH3CH2CH2Br"\\implies" EtO(O)CCH(CH3CH2CH2)C(O)OEt
2) EtO(O)CCH(CH3CH2CH2)C(O)OEt 1. + CH3ONa, 2. + CH3J "\\implies" EtO(O)CC(CH3)(CH3CH2CH2)C(O)OEt
3) EtO(O)CC(CH3)(CH3CH2CH2)C(O)OEt + H3O+ "\\implies" HO(O)CC(CH3)(CH3CH2CH2)C(O)OH + 2EtOH
4) HO(O)CC(CH3)(CH3CH2CH2)C(O)OH + heat "\\implies"CH3CH2CH2CH2(CH3)C(O)OH + CO2
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