Question #150656

what is mechanism of action of aciclovir?

Expert's answer

Acyclovir (ACV) is converted to its triphosphate form, acyclovir triphosphate (ACV-TP), which competitively inhibits viral DNA polymerase.

It does this by incorporating into the viral DNA chain and inactivates the viral DNA polymerase thereby terminating the growing viral DNA chain.


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