Question #150102

Explain the mechanism of inhibition of dihydropteroate synthetase by sulphonamides.

Which is the natural substrate?

Expert's answer

Sulfonamides competitive as inhibitors of the enzyme dihydropteroate synthase. They block the synthesis of Tetrahydrofolic acid, thus inhibiting it's formation. They inhibit production of 7,8-dihydropteroate from para-aminobenzoic acid (pABA) and dihydropterin pyrophosphate (DHPP). Para-aminobenzoic acid (pABA) and dihydropterin pyrophosphate (DHPP) are natural substrates.


Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!

Place free inquiry
Calculate the price
Learn more about our help with Assignments: Organic Chemistry
Our fields of expertise
Submit Your Assignment. We Can Do It.
LATEST TUTORIALS
APPROVED BY CLIENTS
"assignmentexpert.com" is professional group of people in Math subjects! They did assignments in very high level of mathematical modelling in the best quality. Thanks a lot
Canada #339914 on Dec 2023