You are responsible for preparing p-guaiacol, a flavoring agent. Your supervisor asks you to make 8.1 g of the compound and you can expect a yield of 77 %. You need to calculate the reagent quantities necessary and choose to use the stoichiometry you learned in experiment 3 of CHEM 266L.
(i) 1 M NaOH/Ethanol is not available, what mass of NaOH(s) should be used instead?
(ii) What mass/volume of hydroquinone should be used?
(iii) What volume of iodomethane (CH3I) should be used?
(iv) Would the SN2 still be possible if methanol and the electrophile below was used instead of p-guaiacol and iodomethane? Briefly explain your answer.
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