Question #72215

What's the polarity of acetylcysteine?

Expert's answer

Answer on Question#72215 – Chemistry – Inorganic chemistry

Question: What's the polarity of acetylcysteine?

Answer:

Acetylcysteine is a derivative of non-polar amino acid cysteine. It has non-polar side chain - CH₂SH as well. However, acetylcysteine is the polar molecule because has polar functional groups (N-acyl group and carboxylic acid group). The distribution of electron density is showed via couple of resonance form of acetylcysteine:



Dipole as measure of polarity is calculated via Molecular calculator (http://molcalc.org) and it equals 4.83 Debye.



Blue: Positive, Red: Negative

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