Answer to Question #329649 in Inorganic Chemistry for Amolai

Question

With the two named examples give the types of bond a drug forms with its receptor at its site of action

Answer 1

Drugs interact with receptors by means of chemical bonds. The three major types of bonds are covalent, electrostatic, and hydrophobic. Covalent bonds are strong and, in many cases, not reversible under biologic conditions. Electrostatic bonds are weaker than covalent bonds, more common, and often reversible. Hydrophobic bonds are the weakest and are probably the most important in the interactions of lipid-soluble drugs and in hydrophobic “pockets” of receptors.