Common aspirin is acetylsalicylic acid, which has the structure shown below and a pKa of 3.5. Calculate the pH of a solution in which one normal adult dose of aspirin (650 mg
mg ) is dissolved in 6.0 ounces of water.
Aspirin is a weak acid.
pH of an weak acid = .5pKa - .5logC
C is the concentration in molarity
Molecular weight of aspirin =180.158 g/mole
650mg = (.650/180.158)moles
= .0036 mole
6 ounce = 177.282 ml
Concentration of the solution = (.0036/.177282) M
=0.02 M
Therefore pH of the solution is
= .5*3.5 - .5log0.02
=0.9
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