cells that use amino acid tryptophan produce which products during the degradation reaction
Tryptophan degradation takes place as a consequence of on-going immune activation, within cellular immune response the enzyme indoleamine-2,3-dioxygenase (IDO) is induced to convert tryptophan to N-formyl-kynurenine (which is then further catabolized to kynurenine).
The body uses tryptophan to help make melatonin and serotonin. Melatonin helps regulate the sleep-wake cycle, and serotonin is thought to help regulate appetite, sleep, mood, and pain. The liver can also use tryptophan to produce niacin (vitamin B3), which is needed for energy metabolism and DNA production.
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