Although the five immunoglobulin isotypes share many common structural features, the differences in their structures affect their biological activities.
i. Draw a schematic diagram of a typical IgG molecule and label each of the following parts: Hchains, L chains, intra chain disulfide bonds, hinge, Fab ,Fc, and all the domains. Indicate which domains are involved in antigen binding.
ii. How would you have to modify the diagram of IgG to depict an IgA molecule isolated from saliva?
iii. How would you have to modify the diagram of IgG to depict serum IgM?
Immunoglobulin A (IgA): It's found in the linings of the respiratory tract and digestive system, as well as in saliva (spit), tears, and breast milk. Immunoglobulin G (IgG): This is the most common antibody. It's in blood and other body fluids, and protects against bacterial and viral infections
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