Answer to Question #157424 in General Chemistry for Marvellous Bamisaye

Question

1. Give four procedures to be followed in search for a "lead" as a drug designer.

2. Give three examples of natural products as leads/protypes for drug development.

3. Give two reasons for chemical modification.

Answer 1

1- Designer drug users typically take the drugs to have feelings of exhilaration, wakefulness, and relaxation In addition to these effects, there are a number of negative effects including but not limited paranoia, decreased appetite, sleepiness hallucinations, panic attacks, aggressive behavior, nausea, blood pressure changes seizures, blackouts, slurred speech, depression aridity, blurred vision, and irritability. In certain instances, the use of designer drugs can lead to death.

2-Drugs which are produced from natural sources.

Common natural sources include plants, animals, microbes etc.

Therapeutic effect of natural products are more compared to synergic drugs

3-.Chemical modification involves the introduction of functional groups into the starch For these reasons, it has not been possible to propose a three-dimensional .The binding site for pyridoxal phosphate in the small subunit