Answer to Question #150659 in General Chemistry for fatima

Question #150659
Describe the mechanism of action of doxorubicin, mention the types of interactions,
structural features
1
Expert's answer
2020-12-21T03:25:48-0500

Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of actionDoxorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation


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