Question #152138
Protein sequence changes in the antibody _______ will change the affinity for a specific epitope.
a. Variable region
b. Nuclear localization domain
c. Intracellular domain
d. Transmembrane domain
e. Constant region
a. Variable region
b. Nuclear localization domain
c. Intracellular domain
d. Transmembrane domain
e. Constant region
Expert's answer
a. Variable region
Protein sequence changes in the antibody variable region will change the affinity for a specific epitope. This region is responsible for the binding to a specific epitope and determines the affinity of the antigen-antibody interaction.
