Answer to Question #4762 in Molecular Biology for Lisa

Question

The net charge of the non-mutated peptide: Met-Lys-Ile-Val-Glu-Asn-Ser-Phe-Ser-Lys-Thr is _____ at neutral pH
a. 0
b. -1
c. +1
d. -2
e. +2

Answer 1

Neutral pH=7

Met (pK_NH2) = 9,21
Lys (pK_R) = 10,53
Glu (pK_R) = 4,25
Thr (pK_COOH) = 2,11

pH=7

Charge = +1(Met)+1(Lys)-1(Glu)+1(Lys)-1(Thr)=+1