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Answer to Question #4762 in Molecular Biology for Lisa
Question #4762
The net charge of the non-mutated peptide: Met-Lys-Ile-Val-Glu-Asn-Ser-Phe-Ser-Lys-Thr is _____ at neutral pH
a. 0
b. -1
c. +1
d. -2
e. +2
a. 0
b. -1
c. +1
d. -2
e. +2
Expert's answer
Neutral pH=7
Met (pKNH2) = 9,21
Lys (pKR) = 10,53
Glu (pKR) = 4,25
Thr (pKCOOH) = 2,11
pH=7
Charge = +1(Met)+1(Lys)-1(Glu)+1(Lys)-1(Thr)=+1
Met (pKNH2) = 9,21
Lys (pKR) = 10,53
Glu (pKR) = 4,25
Thr (pKCOOH) = 2,11
pH=7
Charge = +1(Met)+1(Lys)-1(Glu)+1(Lys)-1(Thr)=+1
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