Answer to Question #172178 in Molecular Biology for Emma

Question

Question 6: From the video describe the phenotype of the SCA1 mouse. Is it similar to symptoms observed in SCA1 patients?

Answer 1

They were viable, and displayed both normal development and a normal life span. In addition, they displayed no ataxic symptoms or neurodegeneration even at 30 months of age.

Yes since SCA1 patients have loss of coordination of the limbs and trunk, unstable gait, dysarthric speech, and nystagmus.