Question

2. All cells of a sick man have 47 chromosomes due to the extra X - chromosome. Indicate the name of this mutation, all possible mechanisms of its occurrence and the likelihood of its transmission to offspring.

Answer 1

Klinefelter syndrome usually occurs as a random event during the formation of reproductive cells (eggs and sperm). An error in cell division called nondisjunction results in a reproductive cell with an abnormal number of chromosomes.

Klinefelter syndrome is not inherited; the addition of an extra X chromosome occurs during the formation of reproductive cells (eggs or sperm) in one of an affected person's parents.