Answer to Question #109207 in Molecular Biology for kylie

Question

A mutation within the promoter region can alter transcription of a gene. Describe how this can happen

Answer 1

A mutation in the promoter region can change the binding site for a transcription factor that normally binds to increase transcription. The mutation could either decrease the ability of the transcription factor to bind, thereby decreasing transcription, or it can increase the ability of the transcription factor to bind, thus increasing transcription.