In November 2024
Answer to Question #94774 in Microbiology for Mark
a base-pair substitution that would produce a silent mutation
at this codon. Identify a base-pair substitution that would
result in a missense mutation at this codon. Identify a base-pair
substitution that would produce a nonsense mutation at this
codon.
DNA- ACA
RNA- UGU
Now silent mutation will occur when there is no change in the amino acid formed. UGU codes for cysteine. If it changes to UGC then still it will code for cysteine a silent mutation.
DNA- ACA
RNA- UGU
amino acid - cysteine
silent mutation-
DNA- ACG
RNA- UGC
AMINO ACID- Cysteine
Missense mutation-
DNA- ACC
RNA- UGG
amino acid- tryptophan
Nonsense mutation
DNA- ACU
RNA- UGA
AMino acid- stop codon
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#339914 on Dec 2023
Comments
Thank you, Mark. You're always welcome!
Thank you so much for the answer and for the clarification
Dear Mark, Yes, you are correct. DNA has no uracil. In its place, thymine is present. So in DNA, the codon would be ACT and not ACU.
I thought there is no Uracil in DNA? Your DNA answer in non sense mutation has Uracil on it? Or I'm wrong?
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