Does adenylate cyclase stimulate or inhibit acid secretion in the stomach?
I am confused about my teacher's notes. "Acid secretion is stimulated by ACh, gastrin and histamine. Histamine stimulates adenylate cyclase which increases cAMP production."
When I looked this up apparently gastrin decreases AC (adenylate cyclase) production. If histamine and gastrin both stimulate acid secretion why does one increase and the other decrease AC?
Also in her notes the acid secretion inhibitors are acid, protein, fat as they cause the secretion of CCK and secretin and these stimulate AC. But I thought AC stimulated acid secretion not inhibited it?
Thank you.
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2018-07-18T08:46:18-0400
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