Name five possible ways whereby infected tissue may be modified to limit the spread of pathogen
1. Physical barrier s itself in the tissue (skin, intercellular contacts, mucosa, blood vessels walls etc)
2. Innate immune response (phagocytosis by macrophages and neutrophils)
3. Adaptive immune response (cytokines and antibodies production)
4. Inflammation leading to further immune response and tissue isolation
5. Activation of coagulation system
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