Shila’s normal blood glucose level is 90 mg/100 ml of blood. After a meal, her blood glucose level tends to rise above normal but during fasting, her blood glucose level is low.
Describe briefly the negative feedback mechanism involved in the regulation of her blood glucose level.
In blood glucose regulation, the hormone insulin plays a key role. When blood glucose level rises in the blood, insulin sends a signal to the liver, muscles and other cells to store the excess glucose. Some is stored as body fat and other is stored as glycogen in the liver and muscles. If the blood glucose level is too low, the pancreas releases the hormone glucagon. This travels to the liver in the blood and causes the break-down of glycogen into glucose. The glucose enters the blood stream and glucose levels increase back to normal.
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