Answer to Question #126658 in Human Anatomy and Physiology for Ramseyer Brace

Question #126658
ATPase is an enzyme that can hydrolyse ATP and release the potential energy stored in the phosphate bond. How would a metabolic inhibitor that blocks ATPase function affect the resting potential of nerve cells?
1
Expert's answer
2020-08-06T03:57:20-0400

The sodium pump is by itself electrogenic, three Na+ out for every two K+ that it imports. So if you block all sodium pump activity in a cell, you would see an immediate change in the membrane potential because you remove a hyperpolarizing current, in other words, the membrane potential becomes less negative.


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