Genetics Answers

Name different types of tumor-associated antigens. Are such antigens generally derived from proteins by mutated genes?

Rabbits have coat colours that are controlled by 4 different alleles in the following pattern: C1=brown, C2=grey, C3=Himalayan, C4=albino. Brown is the most dominant allele, followed by grey, then Himalayan, and albino is the least.

Describe the F1 genotype and phenotype ratios from breeding a Grey rabbit (C2 C3) with a brown rabbit (C1 C4)?

which of the following best describes Transcription?
a) The making of tRNA from a DNA segment.
b) The making of an rRNA strand from a DNA segment.
c) The making of an mRNA strand from a DNA segment.
d) Making a copy of DNA into DNA

What of the following best describes Transcription?

a)The making of tRNA from a DNA segment.
b)The making of an rRNA strand from a DNA segment.
c)The making of an mRNA strand from a DNA segment.
d)Making a copy of DNA into DNA

Fragile X syndrome (F or f) is a dominant X-linked disease that often causes autism or autism like symptoms. Poindexter has Fragile X and marries Allie who does not. Using a Punnet Square give the likelihood of having children with Fragile X.

Poindexter’s genotype _________ phenotype ____________
Allie’s genotype _________ phenotype ____________
Percent of sons with Fragile X _________
Percent of daughters with Fragile X _______

Rh factor (D and d) is a factor located on red blood cells (RBC) of humans: specifically, it is a glycolipid on the RBC membrane. Rh+ has the glycolipid while Rh- does not. It displays simple Mendelian inheritance with Rh+ being dominant. Joe has Rh- blood and his wife Sue has Rh+. They have a child who is Rh+. Show this in a Punnet Square.

A cross where neither of the two alleles is fully dominant over the other.

Somatic cells of a sick man have 46 chromosomes and lack of upper arm of 5-th chromosome. Determine the type of mutation, all possible mechanisms of it’s formation and the probability of it’s inheritance in generations.

The coding strand of DNA molecule has the sequence of nucleotides: CGT-AAG-TTC-CAG-GTA. There is a duplication of the sixth nucleotide in DNA chain. Determine the structure of m-RNA and sequence of amino acids before and after the mutation, using the table of genetic code.

10. In Whos (i.e. inhabitants of Whoville), matings between curly haired individuals and spikey haired individuals produce offspring with a mixture of both curly hairs and spikey hairs. Matings between individuals with a mixture of curly and spikey hairs produce offspring in a ratio of 1 curly: 1 spikey: 2 curly and spikey. Is this an example of incomplete dominance or codominance?

11. Gene H controls the sharpness of spines in a type of cactus. Cactuses with the dominant allele, H, have sharp spines, whereas homozygous recessive hh cactuses have dull spines. At the same time, a second gene, N, determines whether cactuses have spines; homozygous recessive nn cactuses have no spines at all. What is the predicted phenotypic ratio for a cross between a doubly heterozygous cactus (HhNn) and a spineless cactus whose parents both had dull spines?