If the order of the genes on chromosomes before the chromosomal change was A-B-C-D-E-F-G and O-P-Q-R-S-T-U, while after the chromosomal change A-B-C-D-S-T-G and O-P-Q-R-E-F-U, what change the chromosomes have undergone?
Changes that affect the structure of chromosomes can cause problems with growth, development, and function of the body's systems. These changes can affect many genes along the chromosome and disrupt the proteins made from those genes.
Structural changes can occur during the formation of egg or sperm cells, in early fetal development, or in any cell after birth. Pieces of DNA can be rearranged within one chromosome or transferred between two or more chromosomes. The effects of structural changes depend on their size and location, whether gene function is interrupted, and whether any genetic material is gained or lost. Some changes cause health problems, while others may have no effect on a person's health.
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