Answer to Question #98535 in Cell Biology for Abhishek

Question

Giving the example of slime mould amoeba describe the phenomena of intercellular recognition aggregation .

Answer 1

The starving slime mould amoebas begin to secrete portions of cyclic AMP, while others recognize such signal and start to respond to them with the appropriate orientation of movements. They have thousands of new genes activated, and they begin to synthesize many new molecules, including those involved in intercellular adhesion. As a result, the cells of amoebas tightly stick together in chains as the flow of amoebas forms, moving to the centers of aggregation, Cellular adhesion involves several different molecules synthesized only by starving amoebas. It turned out, that the initial adhesion is carried out using a surface glyco-proteins.