Answer to Question #309739 in Cell Biology for PKD

Question

  Has any research been done investigating possible means of reducing the rate

of mtDNA mutation? please explain

Answer 1

Often both the clinician and the prospective heteroplasmic mother will use PND, or more so PGD, to identify embryos harbouring absolutely none of the pathogenic mtDNA mutation. It is also possible to select for fetuses and embryos, and thus prevent disease in the next generation and subsequent transmission.7