In December 2024
Answer to Question #309730 in Cell Biology for PKD
Is the decreased mitophagy observed with age at all related to changes in
lysosome function with age?
Age-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by reactive oxygen species (ROS).
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#339914 on Dec 2023
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