Answer to Question #288995 in Cell Biology for fatima

Question

Within the cell, isocitrate dehydrogenase, an enzyme of the citric acid cycle, is located in the

Answer 1

ICDH is a citric acid or tricarboxylic acid cycle enzyme. Isocitrate undergoes dehydrogenation in the presence of ICDH to form oxalosuccinate. In mammalian tissues, there are two NADP-specific ICDH isoenzymes located in the mitochondria and cytoplasm respectively.