Answer to Question #265716 in Cell Biology for micki

Question

Is it more detrimental to have an extra copy of a large chromosome or an extra copy of a smaller chromosome?

Answer 1

Yes

Chromosomal abnormalities can have many different effects, depending on the specific abnormality. For example, an extra copy of chromosome 21 causes Down syndrome (trisomy 21). Chromosomal abnormalities can also cause miscarriage, disease, or problems in growth or development.