Answer to Question #260429 in Cell Biology for hayrunisa

Question #260429

A new drug is developed which selectively cleaves covalent bonds between two sulfur atoms of non-adjacent amino acids in a polypeptide chain. Which level of protein structure in affected molecules would be most directly affected by the drug?

a. Secondary structure

b. Primary structure

c. Tertiary structure

d. Quaternary syructure


1
Expert's answer
2021-11-09T13:24:01-0500

Among all amino acids, cysteine oxidases from Cystine, where 2 cysteine molecules are linked by covalent bonds to form a disulfide bridge, usually 5 to 6 residues apart.

So, here the new drug is developed which selectively cleaves covalent bonds between two sulfur atoms of non-adjacent amino acids in a polypeptide chain.

The disulfide bridge is on the main interaction stabilizing the Tertiary structure. Hence, this drug Impact the tertiary and quaternary structure (as present in Insulin).


Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!

Comments

No comments. Be the first!

Leave a comment

LATEST TUTORIALS
New on Blog
APPROVED BY CLIENTS