Explain peptide and steroid hormones methods of binding to receptors and effect on cell.
Peptide hormones and growth factors initiate signalling by binding to and activating their cell surface receptors. The activated receptors interact with and modulate the activity of cell surface enzymes and adaptor proteins which entrain a series of reactions leading to metabolic and proliferative signals.
Steroid hormones bind to receptors that form homodimers or heterodimers, migrate to the nucleus, and function as nuclear receptors and transcription factors.
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