Question

Why oogonial cells degenerate?

Answer 1

Oogonal cells die shortly after birth or during the fetal period. It is widely accepted that a female is born in mammals with a fixed number of oogonial cells within the ovaries, which gradually decreases over the years without any chance of renewal. When the oocyte reserve is depleted, the ovarian senescence, which induces what is referred to as women's menopause, quickly begins.