Answer to Question #21334 in Bioinformatics for Paransundar Das

Question

what are the application of poisson distribution in bioinformatics

Answer 1

We can estimate or describe by Poisson distribution, for example:
1. The number of mutations on a strand of DNA per unit length. In other words the mutation distribution on a DNA strand.
2. The number of independent local alignments with score greater than some score S. (Karlin & Altschul, 1990)
3. Statistical significance of experimental data, such as DNA-seq data (Zang C et al 2009, Rashid NU et al 2011)