Answer to Question #119803 in Bioinformatics for Christopher

Question #119803
If you want to find more distant homologs in BLAST search, what scoring matrix would you use?
1
Expert's answer
2020-06-10T10:47:09-0400

BLOSUM62 scoring matrix is used in Blast to identify distant homologs. This scoring matrix target alignments that show 20-30% identity and can be used for sensitive search and analysis of long full-length sequences. As a result, this matrix provides the identification of distant relationships between sequences. 


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