Answer to Question #89205 in Biochemistry for Phiroj Kumar bariha

Question

What are the factors that affect the immune response ? Differentiate between the cellular and humoral immunity

Answer 1

The degree of aggregation of bovine serum albumin has been shown to influence not only the quantity of antibody produced but also the magnitude and increase of the relative binding affinity of the antibodies. Corynebacterium parvum which causes massive lymphoreticular cell proliferation initiates `non-specific' factors in the cellular and humoral immune system enabling aggregate free bovine serum albumin, which normally induces unresponsiveness or hyporesponsiveness, to induce a hyperresponsive state in rabbits. This organism not only augments antibody production but the magnitude and evolution of the relative binding affinity of the antibodies.