Answer to Question #76420 in Biochemistry for AAya

Question #76420
Explain how binding GABA inhibits the production of nerve impulse
1
Expert's answer
2019-02-15T08:56:07-0500

GABA binds to special receptor in postsynaptic membrane. This receptor is called GABAA. GABAA consists of 5 protein subunits and forms chlorine channel. When GABA interacts with GABAA, the chlorine channel opens and chlorine ions pass through membrane into cytoplasm. Therefore membrane potential decreases from -60 mV to -90 mV causing hyperpolarization of postsynaptic membrane. This effect leads to emergence of inhibitory postsynaptic potential that makes a postsynaptic neuron less likely to generate an action potential.


Need a fast expert's response?

Submit order

and get a quick answer at the best price

for any assignment or question with DETAILED EXPLANATIONS!

Comments

No comments. Be the first!

Leave a comment

LATEST TUTORIALS
New on Blog
APPROVED BY CLIENTS