Answer to Question #291361 in Biochemistry for Paul Hackman

Question

2. Consider the following segment of DNA, which is part of a much longer molecules constituting a chromosome:

5'....ATTCGTACGATCGACTGACTGACAGTC...3'

3'....TAAGCATGCTAGCTGACTGACTGTCAG....5'

a. which will be the template for the leading strand?

b. Which strand will be synthesized discontinuously?

c. Which strand will be synthesized as Okazaku fragments?

d. Draw the molecules when the DNA polymerase is halfway along this segment.

e. Draw the two complete daughter molecules.

Answer 1

a)3'....TAAGCATGCTAGCTGACTGACTGTCAG....5

b)lagging strand 5'....ATTCGTACGATCGACTGACTGACAGTC...3