Answer to Question #273476 in Biochemistry for nk123

Question #273476

What is the connection between glucagon and urea cycle?


1
Expert's answer
2021-11-30T23:29:01-0500

Glucagon receptor signalling increases urea cycle activity by activating the cAMP-protein kinase A (PKA)-cAMP response element-binding (CREB) protein-pathway, resulting in transcription of urea cycle enzymes and amino acid transporters, the latter serving to increase substrate availability


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