Answer to Question #24329 in Biochemistry for Jessie

Question

The LD50 of aspirin is 1.1 g/kg for rats. Assuming the same LD50 for humans, what dose of aspirin would be required to kill 50% of people who weigh 130 pounds? Hint: 1.0 kg = 2.2 lb (inexact)

Answer 1

The name LD50 is an abbreviation for "LethalDose, 50%" or median lethal dose. It is the amount of the substance
required (usually per body weight) to kill 50% of the test population.
130 pounds is 59.09 kg

Dose of aspirin would be required to kill 50% of people who weigh
130 pounds is 59.09 kg * 1.1 g/kg = 65 g