Answer to Question #104978 in Biochemistry for Chetanna

Question

write an Adair equation of a protein with four identical, equivalent and independent sites

Answer 1

If [F] represents concentration of free binding site and [B] the concentration of bound sites in steady state, then the assassociation constant for this equilibrium is given by: $K=[B]/[F][S]$

The total number of sites is: $n[P]=[F]+[B]$. The equation therefore becomes,

$r=[B]/[P]= 4K[S]/(1+ K[S])$